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Mendelian randomisation (MR) analysis In the present study, a modified Mendelian randomisation approach was performed to investigate a potential causal relationship 36,65 , in which non-pleiotropic polygenic risk scores (i.e., the valid-PRS) were established as instrument variables of randomised experiments for potential causal inference

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Parliament passes plain tobacco packaging law, regulates vaping Second Opinion: Canada's fight with Big Tobacco is back on At the time, the industry argued that taxes were making cigarettes too expensive, forcing smokers onto the black market to buy cheaper cigarettes a contraband supply which the industry itself helped create