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B12 deficiency may result in neurological issues, anemia, poor bone density, and age-related macular degeneration of the eye

In addition, the amount of cobalt that is naturally contained in food is not significant and would not be enough to act as a doping agent

The early proliferation of Treg cells can be explained by the aberrant production of pro-inflammatory cytokines at earlier stages of infection which can lead to inhibitory immune responses to protect the host

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The timeline of injections can also impact their effectiveness

As the body requires relatively low daily supplements of vitamin B12 compared to its stores, a deficiency often takes years to manifest in adults