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The interaction compromises the structural and functional integrity of the fungal membrane, alters its permeability, and triggers significant electrolyte and small molecule leakage, in turn disrupting normal metabolic processes and ultimately leading to cell death

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As a paradox, inhibition and activation of mitophagy have been observed in obesity and diabetes-related heart disorders, with both exerting bidirectional effects

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Ma H, Wang X, Zhang W, Li H, Zhao W, Sun J, Yang M (2020) Melatonin suppresses ferroptosis induced by high glucose via activation of the Nrf2/HO-1 signaling pathway in type 2 diabetic osteoporosis