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The primary end point for this trial was at 14 weeks, by which point 51% of the patients receiving golimumab 50 mg and 45% of those receiving golimumab 100 mg had achieved an ACR20 response compared with 9% in the placebo arm (Figure 7-15)

The compound could theoretically interact with medications affecting NAD+ metabolism, energy pathways, or the enzymes responsible for its clearance from the body