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Five metabolites (L-acetylcarnitine, L-carnitine, ribonic acid, glucaric acid, and taurine) were significantly increased in a group of patients that received acetazolamide oral administration (Supplementary Fig

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Free radicals cause malondialdehyde levels to rise which causes oxidative stress

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Glucose metabolism modulation ESC affects glucose metabolism via several pathways: boosting glycolytic enzyme activity to increase glucose usage, lowering gluconeogenic enzyme expression to reduce liver glucose production, and facilitating GLUT4 translocation to the plasma membrane in muscle and fat tissue, thereby improving glucose uptake in response to insulin (Garg et al