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However, following multiple overdoses which is the predominant mode of paediatric overdose has been reported [15, 51, 56,57,58]

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DEG analysis of early-stage tumor cells showed that, compared to low- and high-mutant tumor cells, moderate-mutant tumor cells significantly upregulated genes encoding cytosolic ribosomal proteins (RPL and RPS), mitochondrial ribosomal proteins (MRPL and MRPS), and OXPHOS-related proteins (Fig

In the asymptomatic phase (4 months of age), the PINK1 knockout rat model has already exhibited mitochondrial dysfunction-related changes such as metabolic abnormalities, complex I activity-related alterations, and changes in oxygen consumption (196)