glutathione and paracetamol overdose

glutathione and paracetamol overdose Mechanism of toxicity - NUS Faculty of Science Too much paracetamol = dangerous

Name: glutathione and paracetamol overdose Mechanism of toxicity - NUS Faculty of Science Too much paracetamol = dangerous
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Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Paracetamol toxicity Deranged Physiology Liver injury induced by paracetamol and challenges associated with intentional and unintentional use PMC A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 This graphic highlights the critical role of glutathione in protecting Download Scientific Diagram Paracetamol toxicity Biochemical Basis Lecture

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