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Typically, treatment sessions may last anywhere from 30 minutes to several hours, with the frequency of sessions ranging from weekly to every few months

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Following the treatment course, the MASI score of the included patients was increased from 41.7% to 85%, however, the melasma severity scale (MSS) was decreased from moderate (score 2) to mild (score 1) during the treatment course (Kusumawardani et al., 2019)