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Metabolic and nonmetabolic functions of PSAT1 coordinate signaling cascades to confer EGFR inhibitor resistance and drive progression in lung adenocarcinoma

An imbalance of the gut microbiota can lead to immune activation and inflammation, particularly through an increase in pro-inflammatory lipopolysaccharides (LPS), which results in increased production of inflammatory cytokines, such as TNF-, IL-1, and IL-6 (218)

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T2DM was diagnosed according to the 1999 criteria of the World Health Organization ( Data Collection and Definitions Demographic information including age, gender, BMI, and duration of diabetes and drug use data such as of antidiabetic drugs, antihypertensive drugs, and lipid-lowering drugs were retrieved from electronic medical records

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