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'Why smoking impairs the ability to learn about safety is not clear, but one possibility is that smoking changes neurotransmitter balances in the brain, which are necessary for successful safety learning.' Dr Haaker and his colleagues now hope to unravel the mechanism underlying this effect with the hope of developing new treatments and perhaps even new drugs

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In the future, we plan to include crude and partially adjusted risk estimates in our analyses to fully incorporate all available risk estimates, to model the adjusted covariates in a more comprehensive way by mapping the adjusted covariates across all studies comprehensively and systematically, and to develop methods to evaluate additional forms of potential bias

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