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Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies

Liao X, Liu Y, Fu X, Li Y (2020) Postmortem studies of neuroinflammation in autism spectrum disorder: a systematic review

Nrf2 also promotes purine base synthesis through the indirect regulation of phosphoribosyl-pyrophosphate amidotransferase (catalyzes the rate-limiting step in purine biosynthesis), and methylenetetrahydrofolate dehydrogenase 2 (a nuclear-encoded mitochondrial enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities) [50]

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Il participe au recyclage dautres antioxydants comme les vitamines C et vitamine E

The dominant Phormidium genome reflects versatile metabolism and physiology that is specialized for a communal lifestyle under fluctuating redox conditions and light availability