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Short-term E-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic Nadph oxidase (Nox-2)

However, a concerning number of toxic substances including heavy metals, nonmetals, pesticides, polycyclic aromatic hydrocarbons, volatile organic compounds, and many other molecules have been identified in them

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For example, the Federal Trade Commission used to recommend smokers who wouldn't quit to switch to low-tar cigarettes, but the National Cancer Institute found that cigarettes that delivered less nicotine induced smokers to take larger puffs, more puffs per cigarette, and smoke more cigarettes per day

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