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Description

IL-6 is produced by various cell types, including T cells, B cells, monocytes, fibroblasts, and endothelial and synovial cells

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It significantly downregulates the expression of CHS1 and alters the expression profile of other chitin synthase genes, leading to impaired chitin biosynthesis and subsequent cell wall damage in Candida albicans ( Guo et al., 2008

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doi: 10.1016/B978-0-323-85503-7.00004-3 226 Ghafouri-FardSShooreiHNoferestiLHussenBMMoghadamMHBTaheriMet al

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This limitation applies particularly to pharmacological agents that modify AMPK, mTOR, redox signaling, or inflammatory cascades in parallel with autophagy-related processes

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