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The more recently developed Hscore uses partly overlapping criteria and is based on (i) the ferritin level together with (ii) the presence of immunosuppression, (iii) fever, (iv) hepatosplenomegaly, (v) peripheral blood cytopenias, (vi) an increased triglyceride level, (vii) increased fibrinogen level, (viii) increased ASAT level and (ix) hemophagocytosis in the bone marrow [193,194,195,196]