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Compared with GHK, its copper (II)-chelated form shows a more prominent antioxidant and anti-inflammatory effect in both in vitro and in vivo studies

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7), which played a key role in SP@M-mediated RA alleviation

In recent years, GHK-Cu has evolved from a dermatological bioactive ingredient into a representative model system linking coordination chemistry, peptide bioactivity, and biomanufacturing engineering