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J Clin Invest 111:8190 Wittenberg RE, Wolfman SL, De Biasi M, Dani JA (2020) Nicotinic acetylcholine receptors and nicotine addiction: a brief introduction

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It also risks breaking your treatment routine, which can worsen depression and make symptoms harder to manage

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In the aforementioned study exposing human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates [29], the detrimental effects were greater in cells exposed to nicotine-rich condensate than to nicotine-free condensate, suggesting that the possible injurious effects of nicotine should be considered when purchasing e-refills