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An increased risk of severe AG/IM was statistically associated with smoking (OR 9.31, 3.85-22.50/OR 4.91, 1.90-12.68) and high TBA concentrations (OR 2.92, 1.19-7.17/OR 3.28, 1.25-8.62)

As it continues into the second third, the sweetness dies down some with spice, cocoa, leather, earthiness and a touch of black pepper melding well together

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Optionally it can also work with e-cigarettes

However, the available evidence suggests that vaping is a much safer option than smoking