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2024;21(9):e70035

HIGH GT EXPRESSION AND INTRATUMOR DRUG ACTIVATION The high expression of GT within aggressive and drug-resistant tumors implies that GSH-conjugated prodrugs, activated at the cell surface by GT, should be particularly effective against GT-positive tumors

E., & Cohen, S

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Despite their growing impact on individuals and healthcare systems worldwide, clear diagnostic tests and definitive treatments are still lacking

After 3 weeks treatment, mice treated with DOX&IR780@PEG-PCL-SS NPs and near-infrared laser irradiation achieved the best anticancer effect, and the tumor growth was the slowest compared with other groups, indicating that the combined therapy can achieve synergistic inhibition effect for the bladder tumors