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The visual outcome following the natural course of BRVO is well documented.5658 In general, BRVO has a good prognosis: 5060% of eyes have been reported to have a final VA of 20/40 or better even without any treatment.5659 The natural course of BRVO is determined by the site and degree of occlusion, the integrity of arterial perfusion to the affected sector, and the efficiency of the developing collateral circulation.59 Chronic ME and bleeding into the vitreous from neovascularizations account most frequently for a poor final VA.54,58,60 Retinal neovascularization and persistent ME develop in 25% and 60% of eyes, respectively.57,61 Gutman et al.60 found that in the natural course of BRVO, only 14% of eyes with chronic ME retained a VA of 20/40 or better, while 86% had a final VA of 20/50 or worse

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