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NaHC03, CH 2 CI 2 (b) Nal/acetone (if required), (c) CI-CH 2 -OCOCI, base, R3-R4 bridged mono- and/or spirocyclic aminals can be prepared either under acidic or base catalyzed conditions such as similar to or variations of conditions reported in the literature, such as, by, Gomes, P

[DOI] [PubMed] [Google Scholar] 273.Molina y Vedia L, McDonald B, Reep B, Brune B, Di Silvio M, Billiar TR, Lapetina EG

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Interestingly, microglia isolated from whole brains of aged mice (21-months-old) show significantly downregulated expression levels of TREM2 compared to younger mice (Hickman et al., 2013

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