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This activity sustains tumor development by providing metabolic intermediates to refill cancer cells and producing reducing molecules, such as nicotinamide adenine dinucleotide phosphate (NADPH) for different metabolic activities (33-35)

A diverse range of fruits like apple, cherry, plum, pear, apricot and peach are grown in Indian Himalayan regions by farmers but apple is most preferred among them all due to its more economic value 15

Resveratrol mitigates high-fat diet-induced vascular dysfunction by activating the Akt/eNOS/NO and Sirt1/ER pathway

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In total, 10 l of each sample was taken for the protein estimation (BCA assay, Thermo)

The implications of this effect of H 2 S on cellular bioenergetics in the context of cancer are discussed below