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The levels of Fe 2+ in each of tissue sample were calculated based on this standard curve

Importantly, SCFAs regulate neuronal development and activity

PMID: 109 VillarDFrostSDeloukasPTinkerA

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Preclinical studies investigating KD in HD have primarily used transgenic mouse models, such as the R6/2 mice, which express mutant huntingtin and exhibit progressive motor deficits, weight loss, cognitive impairment, and mitochondrial dysfunction, mimicking central functional and metabolic aspects of HD progression [95, 96]