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Because of different protein expression patterns, HCs seem to be the cochlear cells most vulnerable to damage caused by free radicals [62]

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Critically, this remodeling dissociates intramolecular constraints between the N-terminal tail and central Armadillo (ARM) repeat domain, thereby exposing cryptic phosphorylation motifs for GSK3 accessibility

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Glutathione synthetase deficiency can be a mild, moderate or severe disease depending on each individual case