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The APOE 4 allele remains the most significant genetic risk factor, enhancing susceptibility to both amyloid pathology and vascular dysfunction (Kelly et al., 2020) language disturbances (Paolini Paoletti et al., 2021) and impaired daily living (Guo et al., 2022)

This can be especially advantageous for individuals who may struggle with daily pill regimens or frequent injections

Researchers found that these individuals had slower thinking and reaction times, along with white matter lesions linked to dementia

This critical step unblocks the metabolic traffic jam, allowing macronutrients to flow freely into the Krebs cycle to generate life-sustaining ATP

Before wiping, if necessary, expose the area of the body where the injection will be given by moving any clothing, jewelry, etc

This study shows for the first time that Tbx1 haploinsufficiency causes brain metabolic imbalance