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Although transport by SLC22A15 cannot be ruled out as an explanation, it is (at least in humans) expressed at very low levels in the small intestine (Reference Yee, Buitrago and Stecula28) and has a much lower transport efficiency for ergothioneine in comparison with SLC22A4, so unlikely to explain the kinetics reported by Sugiura and colleagues (Reference Sugiura, Kato and Shimizu35)

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