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Competitive radioligand binding studies reveal nanomolar-range affinities, with the compound effectively displacing radiolabelled VEGF-A in receptor saturation experiments

However, therapeutic intervention for the regulation of barrier integrity is an emerging topic and more investigations are essential to understand the role of intestinal barrier integrity in various diseases

Cutaneous and Ocular Toxicology

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Extensive workup was unrevealing for possible infective, inflammatory or endocrine causes except for vitamin B 12 deficiency