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Nevertheless, studies on sepsis have led to improved knowledge useful for the development of future therapeutic targets

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Wnt/-catenin is also a potential therapeutic target for common but refractory diseases such as psoriasis, viral infections, and obesity

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As the activation of both JNK and caspase-3 contributed to TNF-induced cell death with NF-B inhibition, we examined the effects of HFD consumption on the hepatic activation status of JNK and caspase-3 cleavage