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Lions mane mushroom brain benefits earned scientific credibility after a 2020 study found that just 1 gram daily supplementation improved cognitive test scores by a lot in people with mild Alzheimer's disease after 49 weeks

doi: 10.1016/j.jhep.2015.02.050

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Oxidative stress in peripheral blood mononuclear cells from patients with Parkinsons disease: negative correlation with Levodopa dosage

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Human studies using Lactobacillus as a probiotic have often demonstrated decreased body weight and/or body fat in a strain-dependent manner (for a review of human studies, see Crovesy et al., 2017 58 ), suggesting that the NNMTi-and-LD-mediated changes to Lactobacillus relative abundance may be critical to NNMTi-mediated weight loss