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Description

Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice

Over-replacement is associated with symptoms of hyperthyroidism, including palpitations, weight loss, heat intolerance, and osteoporosis from long-term high doses

Sci Hortic (Amsterdam) 247:916

10.1038/s41586-023-06269-0 15 OhS

The actual pharmacokinetic comparisons in humans havent been done

(2020) Effect of combined diclofenac and B vitamins (thiamine, pyridoxine, and cyanocobalamin) for low back pain management: systematic review and meta-analysis