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Although immortalization-related limitations require cautious interpretation, cross-validation with higher-fidelity models and human reference datasets preserves the translational relevance of HMC3-derived findings

In this section, we aim to describe the recent progress of experimental drugs targeting ferroptosis in diabetic animal or cell models

Systemic effects Systemic side effects from GHK-Cu injections are rare in research settings but have been documented

Initial step of B12-dependent enzymatic catalysis: Energetic implications regarding involvement of the one-electron-reduced form of adenosylcobalamin

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The ferroptosis indicator changed significantly on mitochondria, which was not so different with what occurred intracellularly, suggesting that mitochondria may play a critical role in atorvastatin-induced ferroptosis