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Abnormal IGF-1 and GH levels have been proposed to play a key role in obesity [130, 240, 241]

Pain Can be felt in one area or many areas throughout the body Can be made worse when firm pressure is applied to soft tissues, or sometimes with gentle pressure such as a hug Fatigue Muscle weakness Sleep disturbances Mood changes (irritability, anxiety, depression) Difficulty concentrating Brain fog and Memory issues Gastrointestinal issues (constipation, diarrhea, IBS) Sensitivity to bright light, loud sounds, and smells Headaches What causes Fibromyalgia Symptoms

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The International Journal of Biochemistry and Cell Biology 38 (2), 183195