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generated HDX-MS and NMR-based model for the tropomyosin-binding domain of the calponin homology-associated smooth muscle (CHASM) protein, where the CHASM intrinsically disordered N-terminal region interacts with the globular C-terminal calponin homology (CH) domain and the cooperativeness between these regions is required for CHASM binding to smooth muscle tropomyosin (MacDonald et al., 2012)

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Learn More Epithalon Epithalon (Epitalon) Epithalon is a synthetic tetrapeptide based on the natural peptide epithalamin, which is produced by the pineal gland