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Antimicrobial resistance (AMR) can be defined as the capacity of microorganisms, such as bacteria, fungi, parasites, and viruses to survive exposure to antimicrobial agents such as antibiotics, antifungals, antivirals, and antiparasitic, thereby reducing or nullifying treatment efficacy (Tang et al., 2023)

Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor coactivator 1

doi: 10.3390/antiox12050994 18 AlhamarGVinciCFranzeseVTramontanaFLe GouxNLudvigssonJet al

doi: 10.1038/s41467-020-17876-0

The longest clinical trial for NR, involving 10 A-T patients, assessed the effects of up to 500 mg per day of NR supplementation over two years

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