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The primary diagnosis supporting testosterone replacement therapy is E29.1 (Testicular hypofunction)

In addition, it is notable that the uptake of the peptides by the cells is affected by the presence of free C-terminal carboxylic group, because the membrane bound peptides without free C-terminal carboxylic group showed less binding affinity to the cells compared to the soluble (or free) FITC labeled peptides which contain the free C-terminal carboxylic group

the CSF/Serum Biobank at the Central Biomaterialbank of the Charit (ZeBanC) (SCISSOR study) supported by WFL-RF grant # WFL-CB-017/08) and the Else Krner-Fresenius-Stiftung Foundation (grant # EKFS 2012_A32) to JMS and MK

doi: 10.1007/s00702-004-0198-8

J Gerontol A Biol Sci Med Sci 73(4):459467