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Peschel, N., Chen, K

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Early clinical trials conducted in the 1990s and early 2000s utilizing standard, unmodified glutathione powder showed virtually no increase in systemic blood levels or reduction in oxidative stress markers

To summarise, by elucidating how -sitosterol re-activates the FEV-SLC7A11-GPX4 axis to suppress ferroptosis across nematode, cellular and mammalian models, this work seeks to establish a mechanistic foundation for developing safe, multitarget geroprotective agents derived from Alpinia oxyphylla

Glutamate both in neurons and glial cells is synthesized through the tricarboxylic acid cycle and additionally in neurons by the glutamateglutamine cycle, where it is accumulated in vesicles for future release

doi: 10.1136/gut.2010.224407 31 HanYSongMGuMRenDZhuXCaoXet al