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Squadrone S, Brizio P, Mancini C, Pozzi E, Cavalieri S, Abete MC, Brusco A

Physiologically, at the cellular level, Mg 2+ is involved in metabolic pathways acting as an enzyme cofactor, contributes to the regulation of membrane stability, regulates ion channels, and acts as an intracellular signal [200, 201]

doi: 10.1038/ng.694 42 LiXLWuCFWuGS

This study provided additional information on the potential effect of ALCAR on disease progression and survival and adds evidence to justify the use of ALCAR in ALS subjects