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Signs You May Need More Fluids Thirst Dry mouth Dark yellow urine Urinating less often than usual Headache Dizziness Fatigue Muscle cramps Light yellow urine is often a general sign of adequate hydration, although vitamins, medications, and some foods can affect urine color

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doi: 10.1021/acs.molpharmaceut.3c00031 95 GrimmH

Oral administration introduces complications

Diabetes 45 : 91100 Zenobi PD et al

They include (x, x): Paralysis or weakness on one side of the face most patients reported that this as the first thing they noticed when they woke up