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This approach helps to smooth out the concentration curve, minimizing the dramatic peak after dosing and the deep trough before the next dose

When researchers tested AOD-9604 in mice with knocked-out beta-3 receptors, it still increased energy expenditure and fat burning through alternate mechanisms

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Altogether, initial reports of NAD + precursors and exercise in clinical trials, while encouraging in certain instances, are still too inconclusive to directly link an increase in NAD + levels and mitochondrial metabolism to established health benefits in humans

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