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10.1016/j.yexcr.2011.11.008 191 RuhlD.DuT.-T.WagnerE

However, in OA, chronic inflammation and oxidative stress often dysregulate lipid metabolism, leading to increased synthesis and accumulation of n-6 PUFAs such as arachidonic acid and linoleic acid

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However, due to the multi-component synergistic nature of traditional Chinese herbal formulas, the specific active components responsible for these effects remain to be further investigated