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Effects manifest gradually : Weeks 1-2 : better energy during workouts, less post-workout fatigue Weeks 2-4 : improved recovery, first signs on waist circumference Weeks 4-8 : measurable improvement in endurance and fat loss Weeks 8-12 : full effects on body composition and performance Muscle saturation takes several weeks, which is why long-term courses are important (8-12 weeks minimum)

Materials and Methods Experimental Animals and Groups In our study, we raised 120 specific pathogen-free (SPF) grade Wistar male rats (180 20 g weight and 24 weeks old, which is equivalent to 1820 years old in humans) provided by the Experimental Animal Center of the 940th Hospital of Joint Logistics Support force of Chinese Peoples Liberation Army (licence: SCXY (Military) 20120020)

Five kidney cortex images were captured per mouse, and staining was quantified as the percentage of the total area, using ImageJ 1.46r (NIH)

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Smoking is the leading cause of COPD, so quitting is the most crucial step toward preventing or delaying disease progression