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GPX, the most prominent family of enzymes within the glutathione metabolic pathway, can catalyze the reduction of hydrogen peroxide and organic peroxides and convert these harmful oxidants into harmless water or alcohols, thereby mitigating oxidative damage to cells and maintaining the redox balance 40

Previous studies have identified that enzymatic expression of HS3ST2, an enzyme leading to heparan sulfate synthesis, is involved in abnormal phosphorylation of the tau protein ( With regards to SARS-CoV-2, the APOE4 protein was shown to interact with ACE2, specifically downregulating the enzyme

Beyond the Paleolithic Prescription: Incorporating Diversity and Flexibility in the Study of Human Diet Evolution

Zhang X, Liu W, Wei S (2020) Luteolin affects keloid fibroblast proliferation and apoptosis by regulating FRAT1 gene expression

Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice

Yao et al., 2011)