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These thresholds were chosen to balance biological relevance, statistical significance, and clinical translational feasibility

[5]Seneviratne, Uthpala

Ruvkun earned this recognition for his contributions to the discovery of microRNA, a new class of tiny RNA molecules that plays a crucial role in gene regulation (see more on page 5)

2024 Apr;14(4):e1653

PD is characterized by an altered gut microbiota composition, the intestinal barrier, and the enteric neuroimmune system, therefore it is possible that intestinal barrier dysfunction may play a key role in PD development and/or progression