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CeO 2 nanoparticles have been shown to be genotoxic to soybeans at concentrations over 1000 mg/kg (254)

Noteworthy, NP seems to be not only promoted by direct injury to neurons but also by TRP channels mediating damage in the surrounding tissue

In addition, the glutamine metabolism, via TCA cycle, promotes action of NADP + -dependent enzyme, which increases NADPH production, consequently increasing the GSH/GSSG (glutathione reduced/glutathione oxidized) ratio [7]

doi: 10.3390/ph16050676

The potential mechanism of KD is to reduce the availability of glucose to tumor cells, depriving them of energy, inhibiting their proliferation, and tumor growth (82)