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These interventions increase gut metabolites like short-chain fatty acids (SCFAs) and glucagon-like peptide-1 (GLP-1), which may protect dopaminergic neurons via the gut-brain axis

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FEBS Lett 586(15):21122121 Brodeur G, Yau E, Badal K, Collier J, Ramachandran K, Ramakrishnan S (2011) Chemical and physicochemical pretreatment of lignocellulosic biomass: a review

Nonetheless, translation of sulfide-based therapy to clinical practice has been stymied due to the very low therapeutic index of sulfide and the incomplete understanding of endogenous sulfide metabolism