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This scaffold clarifies where modalities overlap mechanistically yet differ in scope, durability, and standardization, providing a basis for explicit comparison and rational combination

2.3 Neurological assessments The behavioral changes observed in rats were categorized into different levels to assess their neurological status

In an oncogenic context, the IGF family regulates a number of biological processes such as cancer cell proliferation, apoptosis, metabolism and protein synthesis, which are closely associated with the activation of PI3K/AKT signaling, which subsequently promotes the transcription of downstream pro-oncogenic target genes such as c-Myc and HIF-1 (77)

Smith and Meissner, 2013)