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Participants in both groups were permitted to continue taking multi-vitamins, probiotics, and other medications/supplements as long as they were not those mentioned in the exclusion criteria (i.e., known to significantly raise glutathione levels)

161 Beyond immune cell recruitment, hepatocyte-derived cholic acid triggers the release of Hedgehog ligands by HSCs, initiating Hedgehog signaling and promoting hepatocyte proliferation

The freeze-dried form is stable at room temperature for short periods during shipping (57 days at 1530C), but long-term storage requires freezer conditions to prevent moisture absorption and slow degradation