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These cytokines can promote cognitive dysfunction as they are able to disrupt the blood-brain barrier (BBB), allowing proinflammatory cytokines (52), cells (such as dendritic, B cells, and T cells) (52), and gut microbes or toxins (355) to translocate into the brain and promote inflammation ( Figure 10 )

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More on the mechanics of day switching below

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Artemisinin is a classic antimalarial drug

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Glutathione lowers free radicals and peroxides, reducing the biochemical activity of melanocytes causing it to interact with dopamine to reduce melanin formation

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The role of Kupffer cells in hepatic diseases

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Transcriptional activation of ENPP2 by FoxO4 protects cardiomyocytes from doxorubicin-induced toxicity

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