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EBioMedicine 43 , 632640 (2019)

Both the AE and AE+N-CUR groups demonstrated a pronounced downregulation of TGF-1 in comparison to tumor control subjects, with the combined treatment exhibiting the most substantial effect

and Phenylalanine, Methylfolate and S-Adenosyl-Methionine (SAMe) for neurotransmitter and dopamine support

Because Arg67 is the ligand that directly interacts with MDSA, the R67A mutant demonstrated activity that was notably less inhibited by MDSA, with an IC 50 value of 185 M, which was over 300-fold that of the WT (Table 1)

and bone morphogenic protein-12 (BMP-12) and TGF1 [65])

ChemBioChem 21 , 938942 (2020)