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The side effects of smoked Cannabis were similar to oral delta-9-THC with the addition of unacceptable levels of feeling high in some subjects [80]

Apart from clearance functions, high levels of acidification in synapses are also required for synaptic vesicle fusion and recycling 106 during neurotransmitter exocytic release 107 , which may explain why lysosomal enhancement via pH correction ameliorates synaptic dysfunction and cognition, as well as clearance of aggregate-prone proteins, in mouse models of AD and PD 94,108,109

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Our treatment can be used for all forms of traumatic brain injuries, though the length and type of treatment can vary based on the particular injury

2012;11:M112.017558

Cell Stem Cell 27 , 366382.e7 (2020)