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Altered steroidogenic function in LCs is also indicated by increased levels of 5-reductase, the presence of immature LCs in the adult testis, and modified ratios of 3-androstanediol to testosterone [93]

Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, et al

Artificial light at night and night-shift work: emerging threats for human health

236 Bacteria-derived lipopolysaccharide (which is a canonical PAMP often used to instigate reactive astrogliosis and microgliosis) act as agonists of TLR2 and 4

It exhibits a range of pharmacological effects, including inhibiting platelet aggregation, reducing inflammation, acting as an antioxidant, and scavenging free radicals ( 2+ , while simultaneously increasing the activities of antioxidative enzymes GPX4 and SOD, and FITH1 ( Astragaloside IV (PubChem CID:13943297) is a lanolin alcohol-derived tetracyclic triterpene saponin extracted from Astragalus membranaceus